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Effect of lipid-based nutrient supplements on morbidity among children with stunting: secondary analysis of a randomized trial in Uganda

by Rolland Mutumba
April 1, 2025
in Food, Malnutrition, Nutrition, Stunting
Reading Time: 34 mins read
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Effect of lipid-based nutrient supplements on morbidity among children with stunting: secondary analysis of a randomized trial in Uganda
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  • United Nations Children’s Fund, World Health Organization, World Bank. UNICEF-WHO-World Bank: Joint Child Malnutrition Estimates (JME)-2023 edition interactive dashboard. United Nations Children’s Fund (UNICEF); 2023. Available from: https://data.unicef.org/resources/unicef-who-world-bank-joint-child-malnutrition-estimates-2023-edition-interactive-dashboard-2/.

  • Perin J, Mulick A, Yeung D, Villavicencio F, Lopez G, Strong KL, et al. Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet Child Adolesc Health. 2022;6:106–15.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Black RE, Victora CG, Walker SP, Bhutta ZA, Christian P, de Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013;382:427–51.

    PubMed 

    Google Scholar
     

  • Schlaudecker EP, Steinhoff MC, Moore SR. Interactions of diarrhea, pneumonia, and malnutrition in childhood: recent evidence from developing countries. Curr Opin Infect Dis. 2011;24:496–502.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ibrahim MK, Zambruni M, Melby CL, Melby PC. Impact of Childhood Malnutrition on Host Defense and Infection. Clinical Microbiol Rev. 2017;30:919–71.

    CAS 

    Google Scholar
     

  • Mutumba R, Pesu H, Mbabazi J, Greibe E, Olsen MF, Briend A, et al. Correlates of Iron, Cobalamin, Folate, and Vitamin A Status among Stunted Children: A Cross-Sectional Study in Uganda. Nutrients. 2023;15:3429.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Prendergast AJ, Humphrey JH. The stunting syndrome in developing countries. Paediatrics Int Child Health. 2014;34:250–65.


    Google Scholar
     

  • Checkley W, Buckley G, Gilman RH, Assis AM, Guerrant RL, Morris SS, et al. Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol. 2008;37:816–30.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gibson RS, Bailey KB, Gibbs M, Ferguson EL. A review of phytate, iron, zinc, and calcium concentrations in plant-based complementary foods used in low-income countries and implications for bioavailability. Food Nutr Bull. 2010;31:S134–46.

    PubMed 

    Google Scholar
     

  • LĂłpez-Moreno M, GarcĂ©s-RimĂłn M, Miguel M. Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe?. J Funct Foods. 2022;89:104938.


    Google Scholar
     

  • Miller V, Reedy J, Cudhea F, Zhang J, Shi P, Erndt-Marino J, et al. Global, regional, and national consumption of animal-source foods between 1990 and 2018: findings from the Global Dietary Database. Lancet Planet health. 2022;6:e243–e56.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Beal T, Gardner CD, Herrero M, Iannotti LL, Merbold L, Nordhagen S, et al. Friend or Foe? The Role of Animal-Source Foods in Healthy and Environmentally Sustainable Diets. J Nutr. 2023;153:409–25.

    PubMed 

    Google Scholar
     

  • Munteanu C, Schwartz B. The relationship between nutrition and the immune system. Front Nutr. 2022;9:1082500.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Huybregts L, HoungbĂ© F, SalpĂ©teur C, Brown R, Roberfroid D, Ait-Aissa M, et al. The Effect of Adding Ready-to-Use Supplementary Food to a General Food Distribution on Child Nutritional Status and Morbidity: A Cluster-Randomized Controlled Trial. PLOS Med. 2012;9:e1001313.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Luby SP, Rahman M, Arnold BF, Unicomb L, Ashraf S, Winch PJ, et al. Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Bangladesh: a cluster randomised controlled trial. Lancet Glob Health. 2018;6:e302–e15.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Smuts CM, Matsungo TM, Malan L, Kruger HS, Rothman M, Kvalsvig JD, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2019;109:55–68.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Unger SA, Drammeh S, Hasan J, Ceesay K, Sinjanka E, Beyai S, et al. Impact of fortified versus unfortified lipid-based supplements on morbidity and nutritional status: A randomised double-blind placebo-controlled trial in ill Gambian children. PLOS Med. 2017;14:e1002377.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mangani C, Ashorn P, Maleta K, Phuka J, Thakwalakwa C, Dewey K, et al. Lipid-Based Nutrient Supplements Do Not Affect the Risk of Malaria or Respiratory Morbidity in 6- to 18-Month-Old Malawian Children in a Randomized Controlled Trial. J Nutr. 2014;144:1835–42.

    CAS 
    PubMed 

    Google Scholar
     

  • Bendabenda J, Alho L, Ashorn U, Cheung YB, Dewey KG, Vosti SA, et al. The effect of providing lipid-based nutrient supplements on morbidity in rural Malawian infants and young children: a randomized controlled trial. Public Health Nutr. 2016;19:1893–903.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Barbosa-Silva MC, Barros AJ. Bioelectrical impedance analysis in clinical practice: a new perspective on its use beyond body composition equations. Curr Opin Clin Nutr Metab Care. 2005;8:311–7.

    PubMed 

    Google Scholar
     

  • Norman K, Stobäus N, Pirlich M, Bosy-Westphal A. Bioelectrical phase angle and impedance vector analysis-clinical relevance and applicability of impedance parameters. Clin Nutr. 2012;31:854–61.

    PubMed 

    Google Scholar
     

  • Da Silva BR, Orsso CE, Gonzalez MC, Sicchieri JMF, Mialich MS, Jordao AA, et al. Phase angle and cellular health: inflammation and oxidative damage. Rev Endocr Metab Disord. 2023;24:543–62.

    PubMed 

    Google Scholar
     

  • Mbabazi J, Pesu H, Mutumba R, Filteau S, Lewis JI, Wells JC, et al. Effect of milk protein and whey permeate in large quantity lipid-based nutrient supplement on linear growth and body composition among stunted children: A randomized 2 Ă— 2 factorial trial in Uganda. PLOS Med. 2023;20:e1004227.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Erhardt JG, Estes JE, Pfeiffer CM, Biesalski HK, Craft NE. Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. J Nutr. 2004;134:3127–32.

    CAS 
    PubMed 

    Google Scholar
     

  • Leroy J. ZSCORE06: Stata module to calculate anthropometric z-scores using the 2006 WHO child growth standards. Boston College Department of Economics: Statistical Software Components; 2011.

  • Null C, Stewart CP, Pickering AJ, Dentz HN, Arnold BF, Arnold CD, et al. Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Kenya: a cluster-randomised controlled trial. Lancet Glob Health. 2018;6:e316–e29.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Adu-Afarwuah S, Young RR, Lartey A, Okronipa H, Ashorn P, Ashorn U, et al. Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Does Not Increase Child Morbidity in a Semiurban Setting in Ghana: A Secondary Outcome Noninferiority Analysis of the International Lipid-Based Nutrient Supplements (iLiNS)–DYAD Randomized Controlled Trial. J Nutr. 2020;150:382–93.

    PubMed 

    Google Scholar
     

  • Nyeko R, Kalyesubula I, Mworozi E, Bachou H. Lactose intolerance among severely malnourished children with diarrhoea admitted to the nutrition unit, Mulago hospital, Uganda. BMC Pediatr. 2010;10:31.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Grenov B, Briend A, Sangild PT, Thymann T, Rytter MH, Hother AL, et al. Undernourished Children and Milk Lactose. Food Nutr Bull. 2016;37:85–99.

    PubMed 

    Google Scholar
     

  • Jaeggi T, Kortman GAM, Moretti D, Chassard C, Holding P, Dostal A, et al. Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants. Gut. 2015;64:731–42.

    CAS 
    PubMed 

    Google Scholar
     

  • Paganini D, Zimmermann MB. The effects of iron fortification and supplementation on the gut microbiome and diarrhea in infants and children: a review. Am J Clin Nutr. 2017;106:1688s–93s.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lapić I, Padoan A, Bozzato D, Plebani M. Erythrocyte Sedimentation Rate and C-Reactive Protein in Acute Inflammation: Meta-Analysis of Diagnostic Accuracy Studies. Am J Clin Pathol. 2019;153:14–29.


    Google Scholar
     

  • Raiten DJ, Ashour FAS, Ross AC, Meydani SN, Dawson HD, Stephensen CB, et al. Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE)1, 2, 2, 3, 4, 5. J Nutr. 2015;145:1039S–108S.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Thurnham D. Interactions between nutrition and immune function: Using inflammation biomarkers to interpret micronutrient status. Proc Nutr Soc. 2013;73:1–8.

    PubMed 

    Google Scholar
     

  • Syed S, Manji KP, McDonald CM, Kisenge R, Aboud S, Sudfeld C, et al. Biomarkers of Systemic Inflammation and Growth in Early Infancy are Associated with Stunting in Young Tanzanian Children. Nutrients. 2018;10:1158.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • DeBoer MD, Scharf RJ, Leite AM, FĂ©rrer A, Havt A, Pinkerton R, et al. Systemic inflammation, growth factors, and linear growth in the setting of infection and malnutrition. Nutrition. 2017;33:248–53.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kyle UG, Bosaeus I, De Lorenzo AD, Deurenberg P, Elia M, GĂłmez JM, et al. Bioelectrical impedance analysis-part I: review of principles and methods. Clin Nutr. 2004;23:1226–43.

    PubMed 

    Google Scholar
     

  • Christaki EV, Pervanidou P, Papassotiriou I, Bastaki D, Valavani E, Mantzou A, et al. Stress, Inflammation and Metabolic Biomarkers Are Associated with Body Composition Measures in Lean, Overweight, and Obese Children and Adolescents. Children. 2022;9:291.

  • Mathai JK, Liu Y, Stein HH. Values for digestible indispensable amino acid scores (DIAAS) for some dairy and plant proteins may better describe protein quality than values calculated using the concept for protein digestibility-corrected amino acid scores (PDCAAS). Br J Nutr. 2017;117:490–9.

    CAS 
    PubMed 

    Google Scholar
     

  • Lin T, Meletharayil G, Kapoor R, Abbaspourrad A. Bioactives in bovine milk: chemistry, technology, and applications. Nutr Rev. 2021;79:48–69.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Samtiya M, Samtiya S, Badgujar PC, Puniya AK, Dhewa T, Aluko RE. Health-Promoting and Therapeutic Attributes of Milk-Derived Bioactive Peptides. Nutrients. 2022;14:3001.

  • Wells JCK, Williams JE, Quek RY, Fewtrell MS. Bio-electrical impedance vector analysis: testing Piccoli’s model against objective body composition data in children and adolescents. Eur J Clin Nutr. 2019;73:887–95.

    PubMed 

    Google Scholar
     

  • Pickering AJ, Null C, Winch PJ, Mangwadu G, Arnold BF, Prendergast AJ, et al. The WASH Benefits and SHINE trials: interpretation of WASH intervention effects on linear growth and diarrhoea. Lancet Glob Health. 2019;7:e1139–e46.

    PubMed 

    Google Scholar
     




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